{"id":49,"date":"2025-12-30T10:31:31","date_gmt":"2025-12-30T01:31:31","guid":{"rendered":"https:\/\/tsc.clinic\/blog\/?p=49"},"modified":"2025-12-30T10:31:34","modified_gmt":"2025-12-30T01:31:34","slug":"post-49","status":"publish","type":"post","link":"https:\/\/tsc.clinic\/blog\/post-49\/","title":{"rendered":"\uff031\u3000\u5730\u4e2d\u6d77\u98df\u306e\u52e7\u3081"},"content":{"rendered":"\n<p>\u5730\u4e2d\u6d77\u98df\u306e\u5b9a\u7fa9\uff1a\u30a4\u30bf\u30ea\u30a2\u3084\u30ae\u30ea\u30b7\u30e3\u3001\u30b9\u30da\u30a4\u30f3\u306a\u3069\u5730\u4e2d\u6d77\u6cbf\u5cb8\u306e\u4f1d\u7d71\u7684\u306a\u98df\u7fd2\u6163\u3067\u3001<mark><mark style=\"background-color:#ffffff\" class=\"has-inline-color has-black-color\">\u91ce\u83dc\u3084\u679c\u7269\u3001\u8c46\u985e\u3001\u5168\u7c92\u7a40\u7269\u3001\u9b5a\u4ecb\u985e\u306a\u3069\u3092\u8c4a\u5bcc\u306b\u6442\u53d6\u3057\u3001<\/mark><mark><mark style=\"background-color:#ffffff\" class=\"has-inline-color has-black-color\">\u30aa\u30ea\u30fc\u30d6\u30aa\u30a4\u30eb\u4e3b\u4f53\u306e\u6cb9\u8102\u3092\u4f7f\u7528\u3057\u3066<\/mark><\/mark><mark style=\"background-color:#ffffff\" class=\"has-inline-color has-black-color\">\u4e73\u88fd\u54c1\u3084\u9d8f\u8089\u306f\u9069\u5ea6\u306b\u3001\u8d64\u8eab\u8089\u3084\u7518\u3044\u3082\u306e\u306f\u63a7\u3048\u3081\u306b\u3059\u308b\u98df\u4e8b\u6cd5<\/mark><\/mark>\u3067\u3001\u5341\u5206\u306a\u6c34\u306e\u6442\u53d6\u3068\u98df\u4e8b\u3068\u4e00\u7dd2\u306b\u9069\u5ea6\u306a\u30ef\u30a4\u30f3\u3092\u3068\u308a\u3001\u4eba\u3068\u4e00\u7dd2\u306b\u98df\u4e8b\u3092\u697d\u3057\u3080\u751f\u6d3b\u7fd2\u6163\u3092\u3044\u3046\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"528\" height=\"600\" src=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/199db4309ed6ef50102a80768298ad3a-528x600.jpg\" alt=\"\" class=\"wp-image-51\" srcset=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/199db4309ed6ef50102a80768298ad3a-528x600.jpg 528w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/199db4309ed6ef50102a80768298ad3a-264x300.jpg 264w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/199db4309ed6ef50102a80768298ad3a.jpg 633w\" sizes=\"auto, (max-width: 528px) 100vw, 528px\" \/><figcaption class=\"wp-element-caption\">Screenshot<\/figcaption><\/figure>\n\n\n\n<p>https:\/\/oldwayspt.org\/explore-heritage-diets\/mediterranean-diet<\/p>\n\n\n\n<p>\u548c\u98df\u306e\u5b9a\u7fa9\uff1a\u7c73\u3001\u9b5a\u3001\u91ce\u83dc\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u4f1d\u7d71\u7684\u306a\u65e5\u672c\u6599\u7406\u3067\u30e6\u30cd\u30b9\u30b3\u7121\u5f62\u6587\u5316\u907a\u7523\u306b\u6307\u5b9a\u3055\u308c\u3066\u3044\u308b\u3002\u6d77\u3084\u5c71\u3001\u7551\u306a\u3069\u3067\u7372\u3089\u308c\u308b\u65b0\u9bae\u306a\u65ec\u306e\u98df\u6750\u3092\u6d3b\u304b\u3059\uff1a\u523a\u8eab\u3001\u5bff\u53f8\u3001\u5929\u3077\u3089\u306a\u3069<\/p>\n\n\n\n<p>\u65e5\u672c\u98df\u306e\u5b9a\u7fa9\uff1a\u548c\u98df\u3092\u542b\u3080\u65e5\u672c\u3067\u98df\u3079\u3089\u308c\u308b\u5168\u3066\u306e\u6599\u7406\u3092\u6307\u3059\u3002\u6d77\u5916\u304b\u3089\u4f1d\u308f\u3063\u3066\u65e5\u672c\u98a8\u306b\u30a2\u30ec\u30f3\u30b8\u3055\u308c\u305f\u3082\u306e\u3082\u542b\u3080\u3002<\/p>\n\n\n\n<p>\u5730\u4e2d\u6d77\u98df\u306e\u52b9\u80fd\u6a5f\u5e8f\uff1a\u6162\u6027\u708e\u75c7\u306b\u95a2\u9023\u3059\u308b\u8907\u6570\u306e\u4ee3\u8b1d\u7d4c\u8def\u3092\u901a\u3058\u3066\u5168\u8eab\u6027\u306e\u708e\u75c7\u3068\u9178\u5316\u30b9\u30c8\u30ec\u30b9\u3092\u8efd\u6e1b\u3059\u308b\u3002\u2460\u6297\u9178\u5316\u30d3\u30bf\u30df\u30f3\uff08\u03b2-\u30ab\u30ed\u30c6\u30f3\u3001\u30d3\u30bf\u30df\u30f3C\u3001\u30d3\u30bf\u30df\u30f3E\u306a\u3069\uff09\u3001\u2461\u30dd\u30ea\u30d5\u30a7\u30ce\u30fc\u30eb\u3001\u305d\u3057\u3066\u2462\u30ea\u30dd\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u9178\u5316\u3092\u6291\u5236\u3057\u3066\u708e\u75c7\u8a98\u767a\u30de\u30fc\u30ab\u30fc\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u690d\u7269\u5316\u5b66\u7269\u8cea\u306e\u542b\u6709\u91cf\u304c\u9ad8\u3044\uff08<em>Br J Clin Pharmacol<\/em>. 2017;83(1):114-128. doi:<a href=\"https:\/\/dx.doi.org\/10.1111\/bcp.12986\">10.1111\/bcp.12986<\/a>\uff09\u3002\u30aa\u30ea\u30fc\u30d6\u30aa\u30a4\u30eb\u306b\u542b\u307e\u308c\u308b\u30aa\u30ec\u30aa\u30ab\u30f3\u30bf\u30fc\u30eb\u306b\u3088\u308b\u30b7\u30af\u30ed\u30aa\u30ad\u30b7\u30b2\u30ca\u30fc\u30bc\u963b\u5bb3\u3084\u8102\u80aa\u5206\u306e\u591a\u3044\u9b5a\u306b\u542b\u307e\u308c\u308b\u30aa\u30e1\u30ac3\u8102\u80aa\u9178\u306b\u3088\u308b\u708e\u75c7\u8a98\u767a\u6027\u30a8\u30a4\u30b3\u30b5\u30ce\u30a4\u30c9\u963b\u5bb3\u306a\u3069\u304c\u6319\u3052\u3089\u308b\uff08<em>Nutrients<\/em>. 2025;17(9):1603. doi:<a href=\"https:\/\/dx.doi.org\/10.3390\/nu17091603\">10.3390\/nu17091603<\/a>\uff09\u3002\u5730\u4e2d\u6d77\u98df\u306f\u8102\u8cea\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u6539\u5584\u3057\u3066\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u3092\u9ad8\u3081\u3001\u514d\u75ab\u6d3b\u6027\u5316\u3068\u30b1\u30e9\u30c1\u30ce\u30b5\u30a4\u30c8\u306e\u5897\u6b96\u306b\u95a2\u4e0e\u3059\u308b\u30db\u30eb\u30e2\u30f3\u304a\u3088\u3073\u6210\u9577\u56e0\u5b50\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u8abf\u7bc0\u3059\u308b\uff08<em>J Gerontol A Biol Sci Med Sci<\/em>. 2018;73(3):318-326. doi:<a href=\"https:\/\/dx.doi.org\/10.1093\/gerona\/glx227\">10.1093\/gerona\/glx227<\/a>\uff09\u3002\u3055\u3089\u306b\u8178\u5185\u7d30\u83cc\u53e2\u306e\u597d\u307e\u3057\u3044\u8abf\u7bc0\u3001\u7279\u306b\u6297\u708e\u75c7\u4f5c\u7528\u3068\u514d\u75ab\u8abf\u7bc0\u4f5c\u7528\u3092\u6301\u3064\u77ed\u9396\u8102\u80aa\u9178\u7523\u751f\u83cc\u306e\u5897\u52a0\u3068\u95a2\u9023\u3057\u3066\u3044\u308b\uff08<em>Mol Nutr Food Res<\/em>. 2017;61(12). doi:<a href=\"https:\/\/dx.doi.org\/10.1002\/mnfr.201700300\">10.1002\/mnfr.201700300<\/a>\uff09\u3002<\/p>\n\n\n\n<p>\u6442\u53d6\u983b\u5ea6\uff1a<\/p>\n\n\n\n<p>\u2460\u6708\u306b\u6570\u56de\uff1a\u725b\u8089\u3001\u8c5a\u8089\u3001\u30b9\u30a4\u30fc\u30c4<\/p>\n\n\n\n<p>\u2461\u9031\u306b\u6570\u56de\uff1a\u9d8f\u5375\u3001\u5375\u3001\u30c1\u30fc\u30ba\u3001\u30e8\u30fc\u30b0\u30eb\u30c8<\/p>\n\n\n\n<p>\u2462\u6bce\u9031\uff12\u56de\u4ee5\u4e0a\uff1a\u9b5a\u3001\u30b7\u30fc\u30d5\u30fc\u30c9<\/p>\n\n\n\n<p>\u2463\u6bce\u65e5\u306e\u98df\u4e8b\uff1a\u91ce\u83dc\u3001\u679c\u7269\u3001\u5168\u7c92\u7c89\u3001\u30aa\u30ea\u30fc\u30d6\u6cb9\u3001\u8c46\u3001\u30ca\u30c3\u30c4\u985e\u3001\u30de\u30e1\u79d1\u690d\u7269\u30fb\u7a2e\u5b50\u3001\u30cf\u30fc\u30d6\u3001\u30b9\u30d1\u30a4\u30b9<\/p>\n\n\n\n<p>\u2464\u6bce\u65e5\u98f2\u3080\uff1a\u6c34<\/p>\n\n\n\n<p>\u2465\u9069\u5ea6\u306b\u98f2\u3080\uff1a\u30ef\u30a4\u30f3<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>NEJM\u5831\u544a\uff1a0~9\u70b9\u306e\u5730\u4e2d\u6d77\u30b9\u30b1\u30fc\u30eb\u304c\u9ad8\u3044\u307b\u3069\u5fc3\u8840\u7ba1\u75be\u60a3\u3084\u764c\u306b\u3088\u308b\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u6e1b\u5c11\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u2460\u30001\u65e5\u306b2\uff5e3\u676f\u4ee5\u4e0a\u306e\u91ce\u83dc\u3092\u6442\u53d6\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u2461\u30001\u65e5\u306b2\uff5e3\u500b\u4ee5\u4e0a\u306e\u679c\u7269\u304a\u3088\u3073\u30ca\u30c3\u30c4\u3092\u6442\u53d6\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u2462\u3000\u9031\u306b2\u56de\u4ee5\u4e0a\u8c46\u985e\u3092\u7a4d\u6975\u7684\u306b\u98df\u3079\u308b\u3002<\/p>\n\n\n\n<p>\u2463\u3000\u9031\u306b2\u56de\u4ee5\u4e0a\u3001\u9b5a\u304a\u3088\u3073\u30b7\u30fc\u30d5\u30fc\u30c9\u3092\u6442\u53d6\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u2464\u30001\u65e5\u306b3\uff5e4\u676f\u4ee5\u4e0a\u306e\u5168\u7c92\u7a40\u7269\u3092\u98df\u3079\u308b\u3002<\/p>\n\n\n\n<p>\u2465\u3000\u6cb9\u8102\u6442\u53d6\u306f\u4e00\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u3068\u591a\u4fa1\u4e0d\u98fd\u548c\u8102\u80aa\u9178\u3092\u4e2d\u5fc3\u3068\u3057\u3001\u7279\u306b\u30aa\u30ea\u30fc\u30d6\u30aa\u30a4\u30eb\u3092\u4e3b\u306a\u8102\u80aa\u6e90\u3068\u3059\u308b\uff081\u65e5\u306b25\uff5e40g\uff09\u3002<\/p>\n\n\n\n<p>\u2466\u3000\u9031\u306b1\u56de\u4ee5\u4e0b\u306b\u8089\u985e\u306e\u6442\u53d6\u91cf\u3092\u6291\u3048\u308b\u3002<\/p>\n\n\n\n<p>\u2467\u3000\u4e73\u88fd\u54c1\u306f\u9069\u5ea6\u306b\u6442\u53d6\u3057\uff081\u65e5\u306b1\uff5e2\u676f\u7a0b\u5ea6\uff09\u3001\u4e3b\u306b\u30c1\u30fc\u30ba\u3084\u30e8\u30fc\u30b0\u30eb\u30c8\u3092\u4e2d\u5fc3\u3068\u3059\u308b\u3002<\/p>\n\n\n\n<p>\u2468\u3000\u30a2\u30eb\u30b3\u30fc\u30eb\u306f\u9069\u91cf\u3067\u3001\u7279\u306b\u98df\u4e8b\u3068\u5171\u306b\u30ef\u30a4\u30f3\u3092\u6442\u53d6\u3059\u308b\uff08\u7537\u6027\u306f1\u65e5\u306b2\u676f\u4ee5\u4e0b\u3001\u5973\u6027\u306f1\u676f\u4ee5\u4e0b\uff09\u3002<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><\/li>\n<\/ol>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"541\" height=\"600\" src=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/7dd4c3f74f006b34bb1d70d7adebd54e-541x600.jpg\" alt=\"\" class=\"wp-image-52\" srcset=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/7dd4c3f74f006b34bb1d70d7adebd54e-541x600.jpg 541w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/7dd4c3f74f006b34bb1d70d7adebd54e-271x300.jpg 271w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/7dd4c3f74f006b34bb1d70d7adebd54e.jpg 823w\" sizes=\"auto, (max-width: 541px) 100vw, 541px\" \/><figcaption class=\"wp-element-caption\">Screenshot<\/figcaption><\/figure>\n\n\n\n<p>\u975e\u5730\u4e2d\u6d77\u98df\u7fa4\uff080~3\u70b9\u30016848\u4eba\uff09\u3001\u4e2d\u9593\u7fa4\uff084~5\u70b9\u30019488\u4eba\uff09\u3001\u5730\u4e2d\u6d77\u98df\u7fa4\uff086~9\u70b9\u30015707\u4eba\uff09\u3002\u8ffd\u8de1\u671f\u9593\u4e2d\u306b275\u4eba\u304c\u6b7b\u4ea1\u3057\u3001\u6027\u5225\u3084\u5e74\u9f62\u3001BMI\u3001\u8eab\u4f53\u6d3b\u52d5\u6027\u306a\u3069\u3067\u88dc\u6b63\u3059\u308b\u3068\u5730\u4e2d\u6d77\u98df\u30b9\u30b3\u30a2\u304c\u9ad8\u3044\u4eba\u307b\u3069\u6b7b\u4ea1\u30ea\u30b9\u30af\u304c\u4f4e\u304b\u3063\u305f\u3002\u5730\u4e2d\u6d77\u98df\u30b9\u30b3\u30a2\u304c\uff12\u30dd\u30a4\u30f3\u30c8\u9ad8\u304f\u306a\u308b\u3068\u3001\u6b7b\u4ea1\u30ea\u30b9\u30af\u306f\uff14\u5206\u306e\uff11\u4f4e\u304f\u306a\u308b\u3068\u63a8\u5b9a\u3055\u308c\u305f\u3002\u6b7b\u56e0\u5225\u3067\u306f\u5fc3\u7b4b\u6897\u585e\u306a\u3069\u51a0\u52d5\u8108\u75be\u60a3\u306b\u3088\u308b\u6b7b\u4ea1\u30ea\u30b9\u30af\u306f33\uff05\u3001\u764c\u306b\u3088\u308b\u6b7b\u4ea1\u30ea\u30b9\u30af\u306f24\uff05\u4f4e\u304f\u306a\u3063\u305f\u3002\u306a\u304a\u500b\u5225\u306e\u98df\u6750\u6442\u53d6\u3068\u6b7b\u4ea1\u30ea\u30b9\u30af\u3068\u306e\u56e0\u679c\u95a2\u4fc2\u306f\u306a\u304b\u3063\u305f\u3002\uff08N Engl J Med\u00a02003;348:2599-2608\u3000DOI: 10.1056\/NEJMoa025039 Vol 348, 26)<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p>JAMA\u5831\u544a\uff1a\u53b3\u5bc6\u306a\u5730\u4e2d\u6d77\u98df\u6442\u53d6\u306e\u4ecb\u5165\u7fa4\u306f\u4e00\u822c\u7684\u306a\u4f4e\u8102\u80aa\u98df\u4e8b\u6307\u5c0e\u7fa4\u3068\u6bd4\u8f03\u3057\u3066PASI\u30b9\u30b3\u30a2\uff08\u91cd\u75c7\u5ea6\u30b9\u30b3\u30a2\uff09\u306e\u5e73\u5747\u306e\u5dee\u306f-3.4(95%CI: -4.8\u301c-2.0, P&lt;0.01\uff09\u3067\u3001PASI75\u6539\u5584\u7387\uff08\u91cd\u75c7\u5ea6\u304c75\uff05\u6539\u5584\u3057\u305f\u5272\u5408\uff0947.4\uff05\u3001\u3055\u3089\u306bHbA1\uff43\u306e\u6709\u610f\u306a\u6e1b\u5c11\u3092\u8a8d\u3081\u305f\uff08-4,1mmol\/mol, 95%CI -6.9~-1.3, P=0.01\uff09\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/f261ee76dd4af09a36d3c143ff2b9ba7-800x450.jpg\" alt=\"\" class=\"wp-image-50\" srcset=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/f261ee76dd4af09a36d3c143ff2b9ba7-800x450.jpg 800w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2025\/12\/f261ee76dd4af09a36d3c143ff2b9ba7-400x225.jpg 400w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><figcaption 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