{"id":117,"date":"2026-01-25T10:51:45","date_gmt":"2026-01-25T01:51:45","guid":{"rendered":"https:\/\/tsc.clinic\/blog\/?p=117"},"modified":"2026-01-25T10:52:45","modified_gmt":"2026-01-25T01:52:45","slug":"post-117","status":"publish","type":"post","link":"https:\/\/tsc.clinic\/blog\/post-117\/","title":{"rendered":"\uff034\u3000\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306f\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u3059\u304b\uff1f"},"content":{"rendered":"\n<p>\u30c8\u30fc\u30bf\u30eb\u30b9\u30ad\u30f3\u30b1\u30a2\u30fb\u30af\u30ea\u30cb\u30c3\u30af\u9280\u5ea7<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/5621deba8a18b839c7a4321764bb05e8-3-600x600.jpeg\" alt=\"\" class=\"wp-image-123\" srcset=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/5621deba8a18b839c7a4321764bb05e8-3-600x600.jpeg 600w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/5621deba8a18b839c7a4321764bb05e8-3-300x300.jpeg 300w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/5621deba8a18b839c7a4321764bb05e8-3.jpeg 1459w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/figure>\n\n\n\n<p>\u6700\u8fd1\u3001\u60a3\u8005\u69d8\u304b\u3089\u300c\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u304c\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u3092\u6e1b\u3089\u3059\u3068\u805e\u304d\u307e\u3057\u305f\u300d\u3068\u3001\u8cea\u554f\u304c\u6765\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u4eca\u56de\u306f\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3068\u8a8d\u77e5\u75c7\u306e\u4e88\u9632\u52b9\u679c\u306b\u3064\u3044\u3066\u516c\u8846\u885b\u751f\u5b66\u7684\u306a\u8ad6\u6587\u3092\u7d39\u4ecb\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"789\" height=\"447\" src=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/7dd4c3f74f006b34bb1d70d7adebd54e-7.jpg\" alt=\"\" class=\"wp-image-118\" srcset=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/7dd4c3f74f006b34bb1d70d7adebd54e-7.jpg 789w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/7dd4c3f74f006b34bb1d70d7adebd54e-7-400x227.jpg 400w\" sizes=\"auto, (max-width: 789px) 100vw, 789px\" \/><\/figure>\n\n\n\n<p>\u53b3\u9078\u3057\u305f21\u4ef6(104,031,186\u540d\u3092\u5bfe\u8c61)\u306e\u8ad6\u6587\u3092\u307e\u3068\u3081\u305f\u30b7\u30b9\u30c6\u30de\u30c6\u30a3\u30c3\u30af\u30ec\u30d3\u30e5\u30fc\u306e\u8ad6\u6587\u3067\u3059\u3002<\/p>\n\n\n\n<p>\u7d50\u8ad6\u3068\u3057\u3066\u306f\u3001\u75ab\u5b66\u7684\u306b\u6210\u4eba\u306b\u5bfe\u3059\u308b\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u3001\u7279\u306b\u5e2f\u72b6\u75b1\u75b9\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3001\u80ba\u708e\u7403\u83cc\u3001Tdap\uff08\u7834\u50b7\u98a8\uff0b\u30b8\u30d5\u30c6\u30ea\u30a2\uff0b\u767e\u65e5\u54b3\uff09\u306b\u5bfe\u3059\u308b\u30ef\u30af\u30c1\u30f3\u63a5\u7a2e\u306f\u3001\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u4f4e\u4e0b\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3001\u3068\u3044\u3046\u7d50\u8ad6\u306b\u81f3\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>Age and Ageing 2025; 54:afaf331\u3000<\/p>\n\n\n\n<figure class=\"wp-block-embed\"><div class=\"wp-block-embed__wrapper\">\nhttps:\/\/doi.org\/10.1093\/ageing\/afaf331\n<\/div><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"783\" height=\"484\" src=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/7dd4c3f74f006b34bb1d70d7adebd54e-9.jpg\" alt=\"\" class=\"wp-image-120\" srcset=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/7dd4c3f74f006b34bb1d70d7adebd54e-9.jpg 783w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/7dd4c3f74f006b34bb1d70d7adebd54e-9-400x247.jpg 400w\" sizes=\"auto, (max-width: 783px) 100vw, 783px\" \/><\/figure>\n\n\n\n<p>\u2605\u5e2f\u72b6\u75b1\u75b9\u30ef\u30af\u30c1\u30f3\uff1a6\u3064\u306e\u7814\u7a76\uff08979,768\u540d\uff1a\u5bfe\u8c61\u7fa49,455,017\u540d\uff09<br>\u5168\u3066\u306e\u578b\u306e\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u309224%\u4f4e\u6e1b\uff08RR 0.76, 95% CI 0.69-0.83)<br>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u8a8d\u77e5\u75c7\u309247\uff05\u4f4e\u6e1b\uff08RR 0.53, 95%CI 0.44-0.64)<\/p>\n\n\n\n<p>\u2605\u7834\u50b7\u98a8\u30fb\u30b8\u30d5\u30c6\u30ea\u30a2\u30fb\u767e\u65e5\u54b3\u30ef\u30af\u30c1\u30f3(Tdap)\u63a5\u7a2e\uff0841,170\u540d\uff1a\u5bfe\u7167\u7fa4165,109\u540d\uff09<br>\u8a8d\u77e5\u75c7\u30ea\u30b9\u30af\u309233%\u4f4e\u6e1b\uff08RR 0.67, 95%CI 0.54-0.83\uff09<br>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30ea\u30b9\u30af\u309242%\u4f4e\u6e1b\uff08RR 0.58, 95%CI 0.46-0.74\uff09<\/p>\n\n\n\n<p>\u2605\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u30ef\u30af\u30c1\u30f3\uff1a9\u3064\u306e\u7814\u7a76\uff082,510,058\u540d\uff1a\u5bfe\u8c61\u7fa47,547,014\u540d\uff09<br>\u8a8d\u77e5\u75c7\u767a\u75c7\u306e\u30ea\u30b9\u30af\u309213\uff05\u4f4e\u6e1b\u3059\u308b\u304c\uff08RR 0.87, 95%CI 0.77-0.99)\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30ea\u30b9\u30af\u4f4e\u4e0b\u3068\u306f\u95a2\u9023\u6027\u306a\u3057\u3002<br>\u8840\u7ba1\u6027\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u309241%\u4f4e\u6e1b\uff08RR 0.59, 95%CI 0.47-0.75\uff09<\/p>\n\n\n\n<p>\u2605\u80ba\u708e\u7403\u83cc\u30ef\u30af\u30c1\u30f3\uff1a3\u4ef6\u306e\u7814\u7a76\uff08276,413\u540d\uff1a\u5bfe\u8c61\u7fa4402,911\u540d\uff09<br>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u309236\uff05\u4f4e\u6e1b\uff08RR 0.64, 95\uff05CI 0.47-0.87\uff09<br>\u8a8d\u77e5\u75c7\u306e\u30ea\u30b9\u30af\u309225\uff05\u4f4e\u6e1b\uff08RR 0.75, 95%CI 0.56-1.00\uff09<\/p>\n\n\n\n<p>\u2605\u30dd\u30ea\u30aa\u30ef\u30af\u30c1\u30f3<br>\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30ea\u30b9\u30af\u309246%\u4f4e\u6e1b\uff08RR 0.54, 95%CI 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class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/2a831ec055ed4fee4e1d0936ea40500d-2-600x600.jpeg\" alt=\"\" class=\"wp-image-121\" srcset=\"https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/2a831ec055ed4fee4e1d0936ea40500d-2-600x600.jpeg 600w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/2a831ec055ed4fee4e1d0936ea40500d-2-300x300.jpeg 300w, https:\/\/tsc.clinic\/blog\/wp-content\/uploads\/2026\/01\/2a831ec055ed4fee4e1d0936ea40500d-2.jpeg 1459w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" 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